Plot from wikipedia.com :In 1969, Pasadena, California, a young Mexican couple rushes to the mansion of wealthy medium Shaun San Dena (Flor de Maria Chahua). Their son had stolen a necklace from a group of gypsies three days prior, and has been complaining about seeing and hearing ethereal creatures. San Dena tries to help the boy in a seance, but she and the boy's parents are attacked by an unseen force, which leads to the floor opening up under the boy when he is pulled into Hell by demonic hands. Dena states: "We will meet again."
In Los Angeles, California, in 2008, loan officer Christine Brown (Alison Lohman) hopes to be promoted to assistant manager over her co-worker Stu Rubin (Reggie Lee). Her boss, Mr. Jacks (David Paymer) advises her to demonstrate that she can make tough decisions to get this job. Christine is constantly thwarted by Stu who proves himself to be quite devious. Stu goes out of his way to show Christine to be incompetent even going as far as ordering lunch when Mr Jacks does in order to belittle her. During this lunch errand Christine vists Clay, her boyfriend, who has just been promoted. He is a keen coin collector and as Chrstine works in a bank she provides him with rare coins found in circulation. On this occasion she hands him one such coin and he lovingly thanks her before placing it in a envelop in his bag for safe keeping. On returning from lunch Stu, once again, tries to belittle Christine by claiming the lunch order is incorrect.
Christine is visited at the bank by Sylvia Ganush (Lorna Raver) who asks for a third extension on her mortgage. To prove herself to Mr. Jacks, Christine denies Ganush the extension. Ganush resorts to begging for help when Christine screams for security. Security guards escort Ganush out with Mr. Jacks complimenting Christine on how she handled the situation.
Upon leaving the bank, Christine is attacked in her car by Ganush. After a violent struggle, Ganush removes a button from Christine's jacket and uses it to place a curse on Christine. Later, Christine's boyfriend, Clay Dalton (Justin Long), tries to comfort her. They pass a fortune teller's store, where they meet the fortune teller Rham Jas (Dileep Rao), who tells Christine that she is being haunted by an evil spirit.
Alone at home, Christine is attacked by the dark spirit causing minor injuries. Clay assumes that Ganush attacked Christine again which Christine denies as she didn't see anyone. That night, Christine has a dream about Mrs.Ganush attacking her in bed. At work the next day, she has a nosebleed, soaking Mr. Jacks. Fleeing work, Christine tries to find Ganush at the home of her granddaughter Ilenka (Bojana Novakovic). Christine learns that Ganush died the previous night, and Ilenka is in the process of holding a memorial service for her. Christine then returns to Rham Jas, who explains that the spirit haunting her is a powerful demon called the Lamia that will torment for three days before taking her to Hell. Rham Jas suggests a sacrifice to appease the demon, which leads to Christine killing her pet kitten. At a dinner party with Clay and his parents, Christine is still tormented by the Lamia, which frightens the Daltons.
Further attacks from Ganush persist, which lead to Christine and Clay deciding to pay $10,000 to enlist the help of the powerful medium Shaun San Dena (Adriana Barraza). San Dena prepares a seance, to trap the Lamia's spirit in a live goat and kill it, vanquishing the spirit. This plan fails as the Lamia attacks Rham Jas and Christine vowing that it will not rest until it takes Christine's soul to Hell. San Dena banishes the Lamia from the seance, but dies in the process. Rham Jas soon tells Christine the only way to get rid of the curse is to give the cursed item to somebody else as a gift, thereby passing the curse on to that person. Christine seals the button in an envelope but during a car journey with Clay she mixes it up, accidentally, with a number of other letters before managing to retrieve it.
Trying to find a recipient, Christine eventually decides to give the button to Ganush (She considers Stu but at the last minute decides she just can't do it). Christine drives to the cemetery where Ganush is buried and digs up her grave. In a torrential downpour, Christine jams the envelope in the old woman's mouth, formally giving it as if it were a gift.
The next day, Christine goes to Los Angeles Union Station to meet Clay, who is preparing to propose to her; they have plans to spend a relaxing weekend in Santa Barbara. As the train approaches, Clay gives her the envelope with the button in it saying she had dropped it in his car earlier. Christine then realises she must have picked up Clay's envelope, from the car, containing the rare coin she had given him a few days ago. Horrified, Christine falls on the train tracks as a train barrels towards her. Right before the train hits her, demonic hands pop out of the ground which then opens up into a fiery hole. Christine screams in terror, but Clay can not assist her as the train passes between them, and all Clay can do is watch in horror as the Lamia's minions take his girlfriend to Hell to burn for eternity. Clay then looks at the button after seeing what happened.
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